Synthesis, spectral studies and antibacterial screening of some novel derivatives of pyrazoline based on chalcones

被引:0
|
作者
Parmar, Kokila A. [1 ]
Vihol, Jayendrasingh R. [1 ]
Dabhi, Yogesh M. [1 ]
Sutariya, Shashikant D. [1 ]
机构
[1] Department of Chemistry, Hemchandracharya North Gujarat University, Patan (N.Gujarat), India
关键词
Hydrazine - Nuclear magnetic resonance spectroscopy;
D O I
暂无
中图分类号
学科分类号
摘要
Pyrazolines are one of the heterocyclic compounds with very important biological activites. In this view, it was proposed to synthesize some novel pyrazolines from chalcones. Here the synthesis of pyrazolines using piperazine chalcones and phenyl hydrazine under basic condition in presence of ethanol. The structures of synthesized were assigned on the basis of elemental analysis, IR and 1H NMR spectroscopy data. These compounds were screened for their anti-bacterial activity.
引用
收藏
页码:1584 / 1588
相关论文
共 50 条
  • [31] Synthesis, DFT Calculations and Spectral Characterization of Novel Pyrimidine and Pyrazoline Derivatives
    Al-Muntaser, Samia M.
    El-Naggar, Abeer M.
    Abdel-Sattar, Nour E. A.
    Khalil, Ali Kh.
    Abbass, Eslam M.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2023, 66 (11): : 611 - 619
  • [32] Synthesis, Spectral Characterization, in Vitro and in Silico Studies of Benzodioxin Pyrazoline derivatives
    Prabha, B.
    Ezhilarasi, M. R.
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2021, 11 (02): : 9126 - 9138
  • [33] A novel reaction of the "Huisgen zwitterion" with chalcones and dienones: An efficient strategy for the synthesis of pyrazoline and pyrazolopyridazine derivatives
    Nair, Vijay
    Mathew, Smitha C.
    Biju, Akkattu T.
    Suresh, Eringathodi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (12) : 2070 - 2073
  • [34] Synthesis and Antibacterial Screening of Novel Derivatives of Embelin
    Subramanian, L.
    Leema, M.
    Pradeep, N. S.
    Joy, B.
    Pillai, Z. S.
    INTERNATIONAL CONFERENCE ON ADVANCES IN MATERIALS AND MANUFACTURING APPLICATIONS (ICONAMMA-2017), 2018, 310
  • [35] Synthesis and QSAR Studies of Novel Pyrazoline Derivatives as Antiproliferative Agent
    Sable, Prafulla Madhukarrao
    Sayyad, Nusrat Bhuru Ali
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2020, 54 (03) : S610 - S619
  • [36] Synthesis, molecular docking Studies, and evaluation of antibacterial and antioxidant activities of pyrazoline derivatives
    Mohammed, Naol
    Mulugeta, Endale
    Garg, Ankita
    Tadesse, Alemu
    RESULTS IN CHEMISTRY, 2024, 8
  • [37] Convenient Synthesis of Novel Chalcone and Pyrazoline Sulfonamide Derivatives as Potential Antibacterial Agents
    Bonakdar, A. P. S.
    Sadeghi, A.
    Aghaei, H. R.
    Beheshtimaal, K.
    Nazifi, S. M. R.
    Massah, A. R.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020, 46 (03) : 371 - 381
  • [38] Synthesis and antibacterial activity of some chalcones and 1,4-oxazipine derivatives
    Bharucha, PB
    Naik, HB
    ASIAN JOURNAL OF CHEMISTRY, 2000, 12 (01) : 318 - 320
  • [39] Convenient Synthesis of Novel Chalcone and Pyrazoline Sulfonamide Derivatives as Potential Antibacterial Agents
    A. P. S. Bonakdar
    A. Sadeghi
    H. R. Aghaei
    K. Beheshtimaal
    S. M. R. Nazifi
    A. R. Massah
    Russian Journal of Bioorganic Chemistry, 2020, 46 : 371 - 381
  • [40] SYNTHESIS AND REACTIONS OF SOME NEW PYRAZOLINES FROM CHALCONES AND THE SCREENING OF THEIR ANTIBACTERIAL ACTIVITIES
    ELHASHASH, MA
    SOLIMAN, FMA
    SOUKA, LM
    SALMAN, ASS
    REVUE ROUMAINE DE CHIMIE, 1995, 40 (01) : 59 - 66