Effects of dietary copper exposure on accumulation, growth, and hematological parameters in Cyprinus carpio

被引：19
作者：
Al-Akel A.S. [1 ]
Al-Balawi H.F.A. [1 ]
Al-Misned F. [1 ]
Mahboobab S. [1 ,2 ]
Ahmad Z. [1 ]
Suliman E.M. [1 ]
机构：
[1] Department of Zoology, College of Science, King Saud University, Riyadh 11451
[2] GC University, Faisalabad
来源：
Toxicological and Environmental Chemistry | 2010年 / 92卷 / 10期
关键词：
Cprinus carpio; Dietary copper; Growth; Hematological parameters; Rna:dna ratio;
D O I：
10.1080/02772248.2010.486230
中图分类号：
学科分类号：
摘要：
The influence of dietary copper (Cu) exposure on accumulation, growth, and hematological parameters was investigated in Cyprinus carpio after sub-chronic ingestion of 0, 250, 500, 750 or 1000mg kg-1 for 60 days. The profile of Cu accumulation among tissues in C. carpio was dependent on the exposure period and Cu concentration. Liver of C. carpio was the predominant storage tissue and the order of Cu accumulation in tissues was liver>intestine> gill>kidney>muscle. Cu concentration at 4125mg kg-1 reduced growth rate, and was inversely related to growth. The RNA:DNA ratios were not affected by exposure and there was no correlation between growth rate and RNA:DNA ratio in liver and muscle. There were no significant effects of exposure on blood parameters except for magnesium. Cu exposure time and dose increased the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) activity levels. © 2010 Taylor & Francis.
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页码：1865 / 1878
页数：13
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