Antibacterial activity studies of Ni and SnO2 loaded Chitosan beads

被引：8
作者：
Ayeshamariam, A. [1 ]
Sankaracharyulu, G.V. [2 ]
Kashif, M. [3 ]
Hussain, S. [4 ]
Bououdina, M. [5 ]
Jayachandran, M. [6 ]
机构：
[1] Department of Physics, Khadir Mohideen College, Adirampattinam
[2] Arignar Anna Government Arts & Science College, Karaikal District, Karaikal
[3] Department of electrical and electronic engineering, Faculty of engineering, Universiti Malayaia Sarawak, Kota Samarahan, 94300, Sarawak
[4] National Engineering Research Centre for Magnesium Alloys, Chongqing
[5] Nanotechnology Centre, Department of Physics, University of Bahrain
[6] Electro Chemical Material Science Division, Central Electro Chemical Research Institute (CSIR), Karaikudi
来源：
Materials Science Forum | 2015年 / 832卷
关键词：
Antibacterial activity; Ni-Chitosan; SnO[!sub]2[!/sub]-Chitosan; Staphylococcus aureus;
D O I：
10.4028/www.scientific.net/MSF.832.110
中图分类号：
学科分类号：
摘要：
In this work, Ni and SnO2 loaded Chitosan nanomaterials are prepared by neutralization method, obtained by drop wise addition of Chitosan solution to a solution of NaOH, followed by cross-linking. The Structural, morphological and Raman analyses are carried out. The antibacterial activity is analysed against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and evaluated by the calculation of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The obtained results show that, Ni-loaded nanoparticles could inhibit the growth of various bacteria better than SnO2. These results revealed that, the exposure of Staphylococcus aureus to the Chitosan nanoparticles led to the disruption of cell membranes and the leakage of cytoplasm. © (2015) Trans Tech Publications, Switzerland.
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页码：110 / 122
页数：12
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