Antimicrobial, antioxidant activities and ADME studies of novel BaSnO3 sulphone cellulose with docking simulation

In this elucidation, we investigated the modification of carboxymethyl cellulose with the p-NO2 sulphonyl chloride in the presence of pyridine as a basic medium to easily cleavage of-HCl which can form the CMC/P-NO2 sulphone which is a novel cellulosic compound and confirmed through the spectral analysis. Furthermore, the adsorption of bimetallic oxide BaSnO3 changes the surface of the cellulosic surface and confirms the physical adsorption through FT-IR and SEM analysis. Additionally, the synthesized cellulosic compounds and Bimetallic oxide exhibited antimicrobial activity and antioxidant activities. The determination of MIC and MBC analysis showed the activity of these CMC sulphones and adsorption of BaSnO3 due to the presence of the nitro group in the para position which increases its action, also the presence of bimetallic oxide of barium stannate increase the activity, additionally, the docking analysis of these compounds was confirmed utilized different protein's and showed different binding affinity.