Nanotechnology allied to nitric oxide release materials for dermatological applications

被引：0
|
作者：
机构：
[1] Exact and Earth Sciences Department, Universidade Federal de São Paulo, CEP 09972-270, Diadema, S.P, Rua Prof Artur Riedel
[2] Chemistry Institute, Biological Chemistry Laboratory, Universidade Estadual de Campinas, Campinas, CEP 13083-970, SP
[3] Center of Natural and Human Sciences, Universidade Federal do ABC, SP
来源：
Seabra, A. B. (amedea.seabra@gmail.com) | 1600年 / Bentham Science Publishers卷 / 08期
关键词：
Antibacterial; Nanoparticles; Nitric oxide; Skin; Topical applications; Wound healing;
D O I：
10.2174/157341312801784159
中图分类号：
学科分类号：
摘要：
It is known that nitric oxide (NO) exerts numerous physiological activities in mammals and it is considered a key mediator in many skin disorders. NO is synthesized in human skin cells where it regulates diverse physiological mechanisms such as dermal blood flow, wound healing, skin pigmentation, and aging. The great challenge of NO-based therapies is to preserve the biological activity of this ephemeral free radical. To this end, new biomaterials have been emerging as platforms for NO release for diverse biomedical applications. This review will discuss the new strategies for releasing/generating controlled amounts of NO for several dermatological applications through the use of nanotechnology. © 2012 Bentham Science Publishers.
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页码：520 / 525
页数：5
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