Bacillus thuringiensis (Bt)-based biopesticide: Navigating success, challenges, and future horizons in sustainable pest control

The global demand for food production is escalating, necessitating innovative approaches to mitigate pest-related crop losses. Conventional pest management using synthetic pesticides has several drawbacks, promoting the search for eco-friendly alternatives such as biopesticides. Among these, Bacillus thuringiensis (Bt)-based biopesticides have emerged as a promising option due to their specificity, sustainability, and safety. This article reviews the success and application of Bt as a biopesticide, analysing its environmental impacts, formulation strategies, marketing trends and associated challenges. The environment impact of Bt is multifaceted, influencing soil ecosystems, plant-associated habitats, and non-target organisms. It interacts dynamically with soil invertebrates and affects both aquatic and terrestrial ecosystems, demonstrating a complex ecological footprint. The market for Bt-based biopesticide is expanding, driven by their proven efficacy and eco-friendliness with projections indicating continued growth. Despite the promising market trends, regulatory hurdles and formulation complexities remain significant obstacles. Addressing these challenges require collaborative efforts to streamline processes and enhance market acceptance. Nonetheless, the future of Bt-based biopesticide appears promising. Ongoing research is focused on advanced formulations, expanding the range of targeted pests and fostering regulatory cooperation, underscoring the pivotal role of Bt-based biopesticide in sustainable agriculture.