Development of an impurity and hydrate form controlling continuous crystallization to telescope a two-step batch recrystallization in the GDC-4379 drug substance process

被引:0
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作者
Morris, Gary [1 ]
Keogh, Aaron P. [2 ]
Farid, Umar [2 ]
Stumpf, Andreas [3 ]
机构
[1] Engineering, APC Ltd., Building 11, Cherrywood Business Park, Loughlinstown,Co. Dublin, Ireland
[2] Chemistry, APC Ltd., Building 11, Cherrywood Business Park, Loughlinstown,Co. Dublin, Ireland
[3] Department of Small Molecule Process Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco,CA,94080, United States
来源
Chemical Engineering Research and Design | 2022年 / 183卷
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摘要
Batch data processing
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页码:608 / 622
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