Peptide-based electrochemical biosensors for the detection of disease biomarkers

被引：0

作者：

Vinod, Devika ^{[1
]}

Sadanandan, Sandhya ^{[2
]}

Rajamani, Rejithamol ^{[1
]}

机构：

[1] Department of Chemistry, Amrita Vishwa Vidyapeetham, Amritapuri, Kollam

[2] Department of Chemistry, School of Advanced Sciences, VIT-AP University, Amaravati

来源：

Biosensors and Bioelectronics: X | 2024年 / 20卷

关键词：

Biomarkers; Cyclic voltammetry; Differential pulse voltammetry; Electrochemical biosensors; Peptides; Square wave voltammetry;

D O I：

10.1016/j.biosx.2024.100531

中图分类号：

学科分类号：

摘要：

The detection of clinically important disease-specific biomarkers such as proteins, nucleic acids, antibodies, enzymes, viruses and circulating tumor cells is essential for understanding their role in disease diagnosis and prognosis. Thus, current clinical research aims at developing a biosensor for the ultrasensitive, reliable, and specific detection of these low-abundant biomolecules in bodily fluids including urine, saliva, and blood. Electrochemical biosensors are powerful devices that make it simple, quick, and affordable the detection of disease biomarkers in clinical diagnostics Peptides epitomize an intriguing group of biorecognition elements that can be linked to electrochemical transducers owing to their stability and selectivity concerning a target analyte. Moreover, they are amenable to facile synthesis and modification with designated functional groups, rendering them appropriate for the creation of innovative architectures for electrochemical biosensing systems. In this review, we provided an outline of the most recent developments in material designs, recognition systems, and strategy advancements related to fabricating peptide-based electrochemical biosensors for disease biomarker detection. © 2024 The Author(s)

引用

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