Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications

被引:0
作者
Wang, Zhiyao [1 ]
Liu, Minggao [1 ]
Zhao, Yundi [1 ]
Chen, Yating [1 ]
Noureen, Beenish [1 ]
Du, Liping [1 ]
Wu, Chunsheng [1 ]
机构
[1] Xi An Jiao Tong Univ, Inst Med Engn, Hlth Sci Ctr, Sch Basic Med Sci,Dept Biophys, Xian 710061, Peoples R China
基金
中国国家自然科学基金;
关键词
organic electrochemical transistor; biosensor; functional device; biomedicine; bioanalysis; CONDUCTIVITY ENHANCEMENT; DIABETES MANAGEMENT; GLUCOSE SENSORS; DRY ELECTRODES; PH; FABRICATION; DOPAMINE; SYSTEMS; CELLS; FILMS;
D O I
10.3390/chemosensors12110236
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Organic electrochemical transistors (OECTs), as an emerging device for the development of novel biosensors, have attracted more and more attention in recent years, demonstrating their promising prospects and commercial potential. Functional OECTs have been widely applied in the field of biosensors due to their decisive advantages, such as high transconductance, easy functionalization, and high integration capability. Therefore, this review aims to provide a comprehensive summary of the most recent advances in the application of functional OECT-based biosensors in biomedicine, especially focusing on those biosensors for the detection of physiological and biochemical parameters that are critical for the health of human beings. First, the main components and basic working principles of OECTs will be briefly introduced. In the following, the strategies and key technologies for the preparation of functional OECT-based biosensors will be outlined and discussed with regard to the applications of the detection of various targets, including metabolites, ions, neurotransmitters, electrophysiological parameters, and immunological molecules. Finally, the current main issues and future development trends of functional OECT-based biosensors will be proposed and discussed. The breakthrough in functional OECT-based biosensors is believed to enable such devices to achieve higher performance, and thus, this technology could provide new insight into the future field of medical and life sciences.
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页数:20
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