Laser powder bed fusion (LPBF) is the most widely used metal additive manufacturing technology, but it still faces challenges in manufacturing efficiency. To address the issue, high-power LPBF (HP-LPBF) which employs kilowatt-level lasers emerges in recent years. In this study, a 4 kW Flat-top laser was used for the HP-LPBF of Ti6Al4V alloy. The samples in as-built state and annealed states (750 degrees C/2h, 850 degrees C/2h, 950 degrees C/2h, 1050 degrees C/2h) were investigated in terms of defects, microstructure, and mechanical properties. Results show that keyhole mode melting is avoided by adopting the Flat-top laser, so the relative density of as-built Ti6Al4V is generally positively correlated with the employed laser energy density. The minimum laser energy density to obtain the high-density (>= 99.9%) sample is 50.0 J/mm3, and the highest build rate is 288 cm3/h. The microstructure in asbuilt state exhibits a unique alternating pattern of "bright bands/dark bands". The dark bands consist of needleshaped alpha ' martensite, while the bright bands consist of needle-shaped alpha+(3, which results from the decomposition of alpha ' under the in-situ annealing effect of the 4 kW Flat-top laser. After annealing at 750 degrees C, most of the residual alpha ' decomposes into needle-shaped alpha+(3. As the annealing temperature increases from 750 degrees C to 1050 degrees C, the microstructure undergoes an evolution from needle-shaped alpha+(3 to lamellar alpha+(3 then to lamellar alpha+(3 with some globular alpha and finally to duplex alpha+(3. An optimum strength-ductility balance is achieved after annealing at 850 degrees C, both the tensile strength and the elongation exceed the standard values of Ti6Al4V forgings.