Recent advances of surface enhanced Raman spectroscopy (SERS) in optical biosensing

被引：6

作者：

Cialla-May, Dana ^{[1
,2
,3
,4
,5
,6
]}

Bonifacio, Alois ^{[7
]}

Markin, Alexey ^{[8
]}

Markina, Natalia ^{[8
]}

Fornasaro, Stefano ^{[9
]}

Dwivedi, Aradhana ^{[1
,2
,3
,4
,5
,6
]}

Dib, Tony ^{[1
,2
,3
,4
,5
,6
]}

Farnesi, Edoardo ^{[4
,5
,6
]}

Liu, Chen ^{[1
,2
,3
,4
,5
,6
]}

Ghosh, Arna ^{[1
,2
,3
,4
,5
,6
]}

Schmitt, Michael ^{[4
,5
,6
]}

Popp, Juergen ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] Leibniz Inst Photon Technol, Albert Einstein Str 9, D-07745 Jena, Germany

[2] Leibniz Hlth Technol, Albert Einstein Str 9, D-07745 Jena, Germany

[3] Leibniz Ctr Photon Infect Res LPI, Albert Einstein Str 9, D-07745 Jena, Germany

[4] Friedrich Schiller Univ Jena, Inst Phys Chem IPC, Helmholtzweg 4, D-07743 Jena, Germany

[5] Friedrich Schiller Univ Jena, Abbe Ctr Photon ACP, Helmholtzweg 4, D-07743 Jena, Germany

[6] Leibniz Ctr Photon Infect Res LPI, Helmholtzweg 4, D-07743 Jena, Germany

[7] Univ Trieste, Dept Engn & Architecture, Via Alfonso Valerio 6, I-34127 Trieste, TS, Italy

[8] Saratov NG Chernyshevskii State Univ, Inst Chem, Astrakhanskaya St 83, Saratov 410012, Russia

[9] Univ Trieste, Dept Chem & Pharmaceut Sci, Via Licio Giorgieri 1, I-34127 Trieste, TS, Italy

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2024年 / 181卷

关键词：

SERS; Surface enhanced Raman; SERS-Based biosensor platforms; Medicine and clinical applications; Environmental monitoring; Food quality; Biological studies; INTRACELLULAR PH; PLATFORM; IDENTIFICATION; PROTEINS;

D O I：

10.1016/j.trac.2024.117990

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Surface-enhanced Raman spectroscopy (SERS) is a powerful biosensing technique that combines molecular fingerprint specificity with high sensitivity, detecting trace amounts using plasmonic-based metallic nanostructured sensor platforms. SERS strategies include direct and indirect, as well as targeted and untargeted methods, depending on sample complexity and target analyte affinity. The development of SERS platforms, such as microfluidic environments, lab-on-a-fiber approaches, and paper-based immunoassays, aims at creating portable systems for point-of-care use in clinical and non-lab settings. Combining SERS with other techniques enhances measurement conditions, miniaturization, and sensitivity. This review summarizes key analytical applications of SERS in biosensing, including medicine, clinical diagnostics, environmental monitoring, food quality assessment, and biological studies.

引用

页数：25

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