Determination of 12 volatile perfluoroalkyl and polyfluoroalkyl substances in leathers by dispersive solid-phase extraction-gas chromatography-mass spec⁃ trometry

A method for the simultaneous determination of 12 perfluoroalkyl and polyfluoroalkyl substances （PFAS）in leathers by dispersive solid-phase extraction（d-SPE）-gas chromatography-mass spectrometry（GC-MS） was developed. The target compounds including 4 kinds of fluorotelomer alcohols （FTOHs），3 kinds of fluorotelomer acrylates（FTAs），and 5 kinds of fluorooctane sulfonamides（FOSAs）. The effects of the extraction conditions，purification method，solvent for constant volume on the extraction efficiency were investigated. The target compounds were extracted at 50 ℃ for 20 min with acetonitril，then 1 mL extracting solution was purified by 100 mg graphitized carbon black（GCB），subsequently detected by GC/MS in the scan ion monitoring（SIM）mode and quantified using the external standard method. The results showed that the 12 kinds of PFAS had good linear relationships in the concentration ranges of 0.02-5.0 mg/L with the correlation coefficients （R2）>0.9990. The average recoveries were in the range of 77.6%-110.5%，with relative standard deviations （RSDs）in the range of 1.5%-11%. The limits of quantification were 0.2 mg/kg. This method could meet the needs for detection of PFAS in leathers. © 2024, Youke Publishing Co.,Ltd. All rights reserved.