Harnessing oleaginous yeast to produce omega fatty acids

被引:4
作者
Lin, Lu [1 ]
Ledesma-Amaro, Rodrigo [2 ,3 ]
Ji, Xiao-Jun [1 ]
Huang, He [1 ,4 ]
机构
[1] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, State Key Lab Mat Oriented Chem Engn, 30 South Puzhu Rd, Nanjing 211816, Peoples R China
[2] Imperial Coll London, Dept Bioengn, London SW7 2AZ, England
[3] Imperial Coll London, Imperial Coll Ctr Synthet Biol, London SW7 2AZ, England
[4] Nanjing Normal Univ, Sch Food Sci & Pharmaceut Engn, 2 Xuelin Rd, Nanjing 210023, Peoples R China
基金
中国国家自然科学基金;
关键词
YARROWIA-LIPOLYTICA;
D O I
10.1016/j.tibtech.2024.03.005
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Omega fatty acids are important for human health. They are traditionally extracted from animals or plants but can be alternatively produced using oleaginous yeast. Current efforts are producing yeast strains with similar fatty acid distributions and powerful lipogenesis capacity. The next step is to further make the process more competitive. © 2024 Elsevier Ltd
引用
收藏
页码:1335 / 1338
页数:4
相关论文
共 50 条
[21]   Using nutritional and oxidative stress to increase content of health-beneficial fatty acids in oleaginous and non-oleaginous yeasts [J].
Padrova, Karolina ;
Kolouchova, Irena ;
Rezanka, Tomas ;
Cejkova, Alena .
CHEMICAL PAPERS, 2016, 70 (10) :1351-1359
[22]   Oleaginous yeast Meyerozyma guilliermondii shows fermentative metabolism of sugars in the biosynthesis of ethanol and converts raw glycerol and cheese whey permeate into polyunsaturated fatty acids [J].
Fabricio, Mariana Fensterseifer ;
Valente, Patricia ;
Zachia Ayub, Marco Antonio .
BIOTECHNOLOGY PROGRESS, 2019, 35 (06)
[23]   Metabolic engineering of Yarrowia lipolytica to produce fatty acids and their derivatives [J].
Wang K. ;
Wang J. ;
Wei P. ;
Ji X. .
Ji, Xiaojun (xiaojunji@njtech.edu.cn), 1600, Materials China (72) :351-365
[24]   Selective uptake of fatty acids by the yeast Yarrowia lipolytica [J].
Papanikolaou, S ;
Aggelis, G .
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2003, 105 (11) :651-655
[25]   A metabolic engineering strategy for producing conjugated linoleic acids using the oleaginous yeast Yarrowia lipolytica [J].
Imatoukene, Nabila ;
Verbeke, Jonathan ;
Beopoulos, Athanasios ;
Taghki, Abdelghani Idrissi ;
Thomasset, Brigitte ;
Sarde, Claude-Olivier ;
Nonus, Maurice ;
Nicaud, Jean-Marc .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2017, 101 (11) :4605-4616
[26]   Oleaginous yeast for biofuel and oleochemical production [J].
Spagnuolo, Michael ;
Yaguchi, Allison ;
Blenner, Mark .
CURRENT OPINION IN BIOTECHNOLOGY, 2019, 57 :73-81
[27]   Valorization of Food Waste by Oleaginous Yeast [J].
Khaligh, Soodeh Salimi ;
Altinbas, Mahmut .
5TH EURASIAN WASTE MANAGEMENT SYMPOSIUM, EWMS 2020, 2020, :368-373
[28]   Oleaginous yeast Yarrowia lipolytica mutants with a disrupted fatty acyl-CoA synthetase gene accumulate saturated fatty acid [J].
Wang, Jinjing ;
Zhang, Borun ;
Chen, Shulin .
PROCESS BIOCHEMISTRY, 2011, 46 (07) :1436-1441
[29]   Recent Advancements and Strategies for Omega-3 Fatty Acid Production in Yeast [J].
Kumari, Priya ;
Sharma, Juhi ;
Khare, Prashant .
JOURNAL OF BASIC MICROBIOLOGY, 2025, 65 (03)
[30]   The oleaginous yeast Starmerella bombicola reveals limitations of Saccharomyces cerevisiae as a model for fatty acid transport studies [J].
Lopez, Jose Manuel Salvador ;
Jezierska, Sylwia ;
Kocabey, Aslihan Ekim ;
Lee, Jungho ;
Schneiter, Roger ;
Van Bogaert, Inge N. A. .
FEMS YEAST RESEARCH, 2022, 22 (01)