CuI-Catalyzed Selenylation of Pyrrolo[2,1-a]isoquinolines and Other Electron-Rich Heteroarenes

被引：0

作者：

Zhou, Jing ^{[1
]}

Han, Jia-Yi ^{[1
]}

Yu, Xin ^{[1
]}

Yang, Liu ^{[1
]}

Jiang, Man ^{[1
]}

Li, Yun-Meng ^{[1
]}

Cui, Hai-Lei ^{[1
]}

机构：

[1] Chongqing Univ Arts & Sci, Coll Chem & Environm Engn, Lab Asymmetr Synth, Chongqing 402160, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 19期

基金：

中国国家自然科学基金;

关键词：

METAL-FREE SYNTHESIS; N-PHENYLSELENOPHTHALIMIDE; ORGANOSELENIUM CHEMISTRY; CYCLIZATION; ALKALOIDS; SELENIUM; DISULFIDES; OXIDATION; INDOLES; REAGENT;

D O I：

10.1021/acs.joc.4c01462

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have established a mild CuI-catalyzed selenylation of pyrrolo[2,1-a]isoquinoline derivatives in the presence of mCPBA (m-chloroperoxybenzoic acid) at ambient temperature. Corresponding organoselenides have been prepared readily in 53-92% yields. This process can also be expanded to the modification of pyrroles, azaindole, and indoles, delivering the desired heterocyclic selenides in moderate to good yields.

引用

页码：14050 / 14060

页数：11

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