Exploring the Role of Poly (N-vinyl pyrrolidone) in Drug Delivery

被引：1
作者：
Mikayilov, E. [1 ]
Tagiyev, D. [1 ]
Zeynalov, N. [1 ]
Tagiyev, Sh. [2 ]
机构：
[1] Minist Sci & Educ Republ Azerbaijan, Dept Nanostruct Met Polymer Catalysts, Inst Catalysis & Inorgan Chem, Baku, Azerbaijan
[2] Azerbaijan Med Univ, Dept Oncol, Baku, Azerbaijan
来源：
CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY | 2024年 / 38卷 / 03期
关键词：
nanoparticles; hydrogels; computational modeling; polyvinylpyrrolidone (PVP); drug delivery; SOLID DISPERSIONS; COMPOSITE MICROPARTICLES; NANOFIBROUS MEMBRANE; HYDROGEL MEMBRANES; PHYSICAL STABILITY; PVP; MICROSPHERES; RELEASE; COPRECIPITATION; MATS;
D O I：
10.15255/CABEQ.2024.2331
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Polyvinylpyrrolidone (PVP) is widely recognized for its hydrophilic properties, making it essential in pharmaceutical and biomedical industries as a carrier material. This review examines PVP-enriched delivery systems, emphasizing their capacity to integrate diverse active agents from both organic and synthetic sources. The versatility of PVP is showcased through its use in different formulations, such as microparticles, nanoparticles, fibrous structures, hydrogels, and tablets, which emphasize its potential in innovative drug delivery mechanisms. The review thoroughly examines the customized morphologies for specific PVP-drug combinations, detailing the active agents, methodologies, and processing parameters used. It discusses the advantages and challenges of these systems, underscoring the polymer's significant role in novel pharmaceutical product development. Overall, this detailed analysis confirms PVP's critical position in advancing drug delivery technologies, showcasing its multifaceted applications and potential for pioneering new treatments.
引用
收藏
页码：185 / 196
页数：12
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