Garlic Extract-Mediated Synthesis of ZnS Nanoparticles: Structural, Optical, Antibacterial, and Hemolysis Studies

被引:19
作者
Alnehia A. [1 ,2 ]
Al-Odayni A.-B. [3 ,4 ]
Al-Hammadi A.H. [1 ]
Alramadhan S.A. [3 ,5 ]
Alnahari H. [1 ]
Saeed W.S. [3 ]
Al-Sharabi A. [2 ]
机构
[1] Department of Physics, Faculty of Sciences, Sana'a University, Sana'a
[2] Department of Physics, Faculty of Applied Sciences, Thamar University, Dhamar
[3] Engineer Abdullah Bugshan Research Department for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh
[4] Department of Chemistry, Faculty of Education, Thamar University, Dhamar
[5] Umm Al-Momineen Maimouna Bint Al-Harth Intermediate School at the National Guard, Al Khobar Education Office, General Directorate of Education Eastern Province, Ministry of Education, Al Khobar
关键词
Antibacterials - Eco-friendly - Fourier transform infrared - Garlic extract - Green synthesis - Haemolysis - Optical- - Synthesised - Zinc sulfide nanoparticles - ZnS nanoparticles;
D O I
10.1155/2023/8200912
中图分类号
学科分类号
摘要
The green synthesis of zinc sulfide nanoparticles (ZnS NPs)-mediated plant extract is gaining importance because of its simplicity, cost-effectiveness, and ecofriendly nature. In this work, ZnS NPs were synthesized using garlic extract as NPs facilitating agent, characterized by Fourier transform infrared, X-ray diffraction, scanning electron microscope, and UV-visible, then their antibacterial and hemocompatibility were assayed. Analysis revealed a cubic phase, 2.33 nm crystallite size, and a 3.75 eV optical bandgap. Bioactivity test against Staphylococcus aureus and Escherichia coli indicated dose-dependent potency closer to that of azithromycin standard drug and more efficient on S. aureus (Gram-positive) than E. coli (Gram-negative) bacteria. Biocompatibility test in terms of erythrocyte hemolysis, in reference to normal saline and water as minimal and maximal controls, confirmed nontoxic substance up to 100 μg/mL as the highest examined concentration and at which a lysis of 2.9% was detected. Therefore, it could be concluded that this biogenic method is effective in producing ZnS NPs with desirable properties for potential biomedical applications. © 2023 Adnan Alnehia et al.
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