Optimization and analysis of sustainable magnesium-based alloy (Mg-Zn-Ca-Y) for biomedical applications

被引：0
作者：
Gholap S.S. [1 ]
Kale K.B. [2 ]
机构：
[1] Department of Mechanical Engineering, Pravara Rural Engineering College Loni, S.P. Pune University, Pune
[2] Department of Mechanical Engineering, Dr. Vitthalrao Vikhe Patil College of Engineering, Ahmednagar, S.P. Pune University, Pune
来源：
Journal of Alloys and Metallurgical Systems | 2024年 / 6卷
关键词：
Biomedical; Degradation; Magnesium alloy; Yttrium;
D O I：
10.1016/j.jalmes.2024.100068
中图分类号：
学科分类号：
摘要：
Due to strength and biodegradability, magnesium (Mg) and its alloys are potential biodegradable implant materials. However, pure Mg corrodes more rapidly in the physiological environment, causing rapid deterioration before bone repair. The discrepancy between bone healing and Mg implant deterioration encourages the development of new Mg alloys with other acceptable alloying elements to achieve the desired high corrosion resistance and mechanical properties. In this work, different concentrations of yttrium (Y), that is, Mg-4zn-0.2ca-xY, (x= 3,6,9,12% wt), are added to Mg-based alloys. The microstructure, mechanical characteristics, corrosion behavior, and biocompatibility of the alloys were carefully investigated. When Y concentrations are high, Mg alloys with Y change significantly. High Y concentrations in Mg alloys containing yttrium (Y) suppress intermetallic phases along grain boundaries and form chemically stable Y oxide layers on the surfaces, changing their microstructures and improving their corrosion resistance. Cytotoxicity analysis showed that human osteoblast cells were not significantly affected by the Y-containing Mg alloys. The benefits of using Y as an alloying element to simultaneously adjust Mg alloys with higher strength and slower deterioration are presented. © 2024 The Authors
引用
收藏
相关论文
共 26 条
  • [1] Myrissa A., Agha N.A., Lu Y., Martinelli E., Eichler J., Szakacs G., Kleinhans C., Willumeit-Romer R., Schafer U., Weinberg A.M., In vitro and in vivo comparison of binary Mg alloys and pure Mg, Mater. Sci. Eng.: C, 61, pp. 865-874, (2016)
  • [2] Pahlevanzadeh F., Bakhsheshi-Rad H.R., Ismail A.F., Aziz M., Chen X.B., Development of PMMA-Mon-CNT bone cement with superior mechanical properties and favorable biological properties for use in bone-defect treatment, Mater. Lett., 240, pp. 9-12, (2019)
  • [3] Kiani F., Wen C., Li Y., Prospects and strategies for magnesium alloys as biodegradable implants from crystalline to bulk metallic glasses and composites—a review, Actabiomaterialia, 103, pp. 1-23, (2020)
  • [4] El-Mahallawy N., Palkowskib H., Klingnerc A., Diaad A., Shoeib M., Effect of 1.0 wt% Zn addition on the microstructure, mechanical properties and bio-corrosion behaviour of micro alloyed Mg-0.24Sn-0.04Mn alloy as biodegradable material, Mater. Today Commun., 24, pp. 1-13, (2020)
  • [5] Vinogradov A., Merson E., Myagkikh P., Linderov M., Brilevsky A., Merson D., Attaining high functional performance in biodegradable Mg-alloys: an overview of challenges and prospects for the Mg-Zn-Ca system, Materials, 16, (2023)
  • [6] Kasaeian-Naeini M., Sedighi M., Hashemi R., Delavar H., Microstructure, mechanical properties and fracture toughness of ECAPed magnesium matrix composite reinforced with hydroxyapatite ceramic particulates for bioabsorbable implants, Ceram. Int., 49, pp. 17074-17090, (2023)
  • [7] Verma A., Ogata S., Magnesium based alloys for reinforcing biopolymer composites and coatings: a critical overview on biomedical materials, Adv. Ind. Eng. Polym. Res., 6, 4, pp. 341-355, (2023)
  • [8] Wang B., Gao W., Pan C., Liu D., Sun X., Effect of the combination of torsional and tensile stress on corrosion behaviors of biodegradable WE43 alloy in simulated body fluid, J. Funct. Biomater., 14, 1-16, (2023)
  • [9] Zhang Q., Zhou T., Guo F., Liu D., In vitro corrosion behavior of As-Cast, T4-treated, and As-extruded Mg-Sn-Zn-Zr alloys in Hank's solution, J. Mater. Eng. Perform., 32, pp. 8299-8313, (2023)
  • [10] Savaedi Z., Motallebi R., Mirzadeh H., Aghdam R.M., Mahmudi R., Superplasticity of fine-grained magnesium alloys for biomedical applications: a comprehensive review, Curr. Opin. Solid State Mater. Sci., 27, 1-26, (2023)
123