Revolutionizing nanozyme technology with metal-organic frameworks: Classification, catalytic mechanisms, regulation and applications in biotechnology

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作者：
Wang, Yiran [1 ,2 ]
Yang, Yaqiong [1 ]
Liu, Jiachen [1 ,2 ]
Zi, Xiangyu [1 ,2 ]
Zhu, Huayue [1 ]
Sun, Xiaolong [1 ]
Miao, Yingjie [1 ]
Fu, Yongqian [1 ]
机构：
[1] Taizhou Key Laboratory of Biomass Functional Materials Development and Application, School of Life Sciences, Taizhou University, Zhejiang Province, Taizhou,318000, China
[2] School of Food Sciences and Pharmaceutical Engineering, Nanjing Normal University, No.1 Wenyuan Road Qixia District, Nanjing,210023, China
来源：
Chemical Engineering Journal | 2024年 / 500卷
关键词：
Nanozymes; particularly those based on metal–organic frameworks (MOFs); have demonstrated remarkable potential in the biotechnological sector owing to their stability; straightforward synthesis; and exceptional catalytic efficiency. As porous materials; MOFs possess a wealth of active sites that can mimic the functions of natural enzymes; thereby attracting significant interest in the realm of bio-catalysis. Enhancing the catalytic performance of MOF-based nanozymes is crucial for expanding and improving their applications. This paper review comprehensively summarizes the classification; catalytic mechanism; and regulation approaches of MOF-based nanozymes over the past five years. Furthermore; the recent applications in biosensing; antibacterial; anti-cancer; and antioxidant biomedical fields were explored. Lastly; the challenges and prospects of this rapidly evolving field are outlined to stimulate further innovative research and drive its ongoing advancement. © 2024 Elsevier B.V;
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