Additively manufactured porous Ti6Al4V Alloy with excellent mechanical properties, corrosion resistance, in vitro and in vivo biocompatibility

被引:0
|
作者
Zhang, Lei [1 ,2 ,3 ]
Hu, Hongyan [4 ]
Wang, Quan [5 ,6 ]
Zhou, Jing [7 ]
Liu, Yan [5 ,6 ]
Li, Zonghao [1 ,3 ]
Zhang, Yonghui [5 ,6 ]
Kui, Zhitong [1 ,3 ]
He, Zhengyuan [1 ,3 ]
Jiang, Yehua [1 ,3 ]
机构
[1] Kunming Univ Sci & Technol, Sch Mat Sci & Engn, Kunming 650093, Peoples R China
[2] China Nonferrous Met Innovat Inst Tianjin Co Ltd, Tianjin 300393, Peoples R China
[3] Natl Local Joint Engn Res Ctr Technol Adv Met Soli, Kunming 650000, Peoples R China
[4] Peking Univ Canc Hosp Yunnan, Tumor Hosp Yunnan Prov, Kunming 650118, Peoples R China
[5] Kunming Med Univ, Sch Stomatol, Kunming 650106, Peoples R China
[6] Affiliated Stomatol Hosp, Kunming 650106, Peoples R China
[7] Kunming Yanan Hosp, Dept Stomatol, Kunming 650051, Peoples R China
基金
中国国家自然科学基金;
关键词
Additive manufacturing; TC4; alloy; Mechanical properties; Biocompatibility; MELTED TI-6AL-4V ALLOY; BEHAVIOR; TITANIUM; MICROSTRUCTURE; STRESS; DESIGN; VITRO;
D O I
10.1016/j.jallcom.2024.176982
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In view of the insufficient bearing capacity of porous Ti6Al4V (TC4) alloy, four kinds of porous TC4 alloys with a wall thickness of 200 mu m and a side length ranging from 400 to 700 mu m were designed and subsequently prepared by Additive Manufacturing (Selective Laser Melting, SLM). The results indicated that the porous TC4 alloy was primarily comprised of alpha' phase and a small amount of beta phase. As the side length increased, the size and volume of the acicular alpha' phase increased while the beta phase decreased. Besides, the dislocation density also increased with the increase of side length. The porous TC4 alloy with a side length of 700 mu m exhibited the maximum dislocation density of 6.07x1014 m2. The yield strength and elastic modulus initially decreased and then increased with the increase of side length. Moreover, the increase in side length induced the decrease of Icorr from 1.807 x 10-6 to 4.777 x 10- 7 A/cm2, especially that sample 7-2 presented the best corrosion resistance with the smallest Icorr value (4.777 x 10- 7 A/cm2). It was observed by in vitro assessment that the optical density (OD) of the porous TC4 alloys surpassed 75 % on days 1, 4, and 7. It was noteworthy that the OD value of the porous TC4 alloys with a side length of 700 mu m surpassed 100 % on day 7. Furthermore, the number of adherent cells displayed an increasing trend with the increase in side length. After implanting into the alveolar bone of rabbits at 12th week, the porous TC4 alloy with a side length of 700 mu m induced bone growth due to a higher percentage of bone volume compared to the dental implant. After 12 weeks of in vivo experiments, the results showed that the porous TC4 alloy could reduce the inflammatory response, promote the growth of bone tissue, and have excellent osteogenic properties.
引用
收藏
页数:14
相关论文
共 50 条
  • [1] Additively manufactured porous Ti6Al4V Alloy with excellent mechanical properties, corrosion resistance, in vitro and in vivo biocompatibility (vol 1009, 176982, 2024)
    Zhang, Lei
    Hu, Hongyan
    Wang, Quan
    Zhou, Jing
    Liu, Yan
    Li, Zonghao
    Zhang, Yonghui
    Kui, Zhitong
    He, Zhengyuan
    Jiang, Yehua
    JOURNAL OF ALLOYS AND COMPOUNDS, 2025, 1010
  • [2] Mechanical Properties and In Vitro Behavior of Additively Manufactured and Functionally Graded Ti6Al4V Porous Scaffolds
    Onal, Ezgi
    Frith, Jessica E.
    Jurg, Marten
    Wu, Xinhua
    Molotnikov, Andrey
    METALS, 2018, 8 (04):
  • [3] Corrosion of an Additively Manufactured Ti6Al4V Alloy in Saline and Acidic Media
    Mora-Sanchez, Hugo
    Collado-Vian, Miguel
    Mohedano, Marta
    Arrabal, Raul
    Matykina, Endzhe
    MATERIALS, 2024, 17 (03)
  • [5] Mechanical and biocompatibility studies on additively manufactured Ti6Al4V porous structures infiltrated with hydroxyapatite for implant applications
    Arivazhagan, Adhiyamaan
    Mani, Kalayarasan
    Kamarajan, Banu Pradheepa
    Aashique, A. G. S. Saai
    Vijayaragavan, S.
    Riju, Arthik A.
    Rajeshkumar, G.
    JOURNAL OF ALLOYS AND COMPOUNDS, 2025, 1010
  • [6] An Investigation of Mechanical Properties of Additively Manufactured Regolith Reinforced Titanium Alloy [Ti6Al4V]
    Afrouzian, Ali
    Traxel, Kellen D.
    Bandyopadhyay, Amit
    METAL-MATRIX COMPOSITES: ADVANCES IN PROCESSING, CHARACTERIZATION, PERFORMANCE AND ANALYSIS, 2022, : 107 - 112
  • [7] Mechanical properties of additively manufactured variable lattice structures of Ti6Al4V
    Traxel, Kellen D.
    Groden, Cory
    Valladares, Jesus
    Bandyopadhyay, Amit
    Keck, W. M.
    MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, 2021, 809
  • [8] Mechanical properties of additively manufactured variable lattice structures of Ti6Al4V
    Traxel, Kellen D.
    Groden, Cory
    Valladares, Jesus
    Bandyopadhyay, Amit
    Materials Science and Engineering: A, 2021, 809
  • [9] Additively Manufactured Porous Ti6Al4V for Bone Implants: A Review
    Koju, Naresh
    Niraula, Suyash
    Fotovvati, Behzad
    METALS, 2022, 12 (04)
  • [10] A review on in vitro/in vivo response of additively manufactured Ti-6Al-4V alloy
    Alipour, Saeid
    Nour, Shirin
    Attari, Seyyed Morteza
    Mohajeri, Mohammad
    Kianersi, Sogol
    Taromian, Farzaneh
    Khalkhali, Mohammadparsa
    Aninwene, George E., II
    Tayebi, Lobat
    JOURNAL OF MATERIALS CHEMISTRY B, 2022, 10 (46) : 9479 - 9534