Characterization and biological studies of copper nanoparticles synthesized by Aspergillus Niger

Nanoparticles synthesis by biological means having large biomedical applications has great importance worldwide. In this study, we synthesized copper nanoparticles and used Aspergillus Niger fermentation filtrate as reducing agent in 1:1 ratio with copper nitrate tri-hydrate solution (Cu(NO3)2 ·3H2O). Synthesized nanoparticles were characterized by various techniques including UV-visible spectrophotometer, FTIR and SEM. The UV-chromatogram of CuNPs appeared between 250-400 nm while FTIR analysis showed absorbance bands at 3264.03-1636.32 cm-1. SEM revealed that CuNPs are spherical and polydisperse in shape with 500 nm in size. We got significant antimicrobial activity of these particles against Escherichia coli, Salmonella typhi, Staphylococcus aureus and Candida albicans. The in vitro α-amylase inhibitory activity of these particles exhibited 40% of anti-diabetic activity. Copyright © 2017 American Scientific Publishers All rights reserved.