Dual-Template Molecularly Imprinted Polymers for Dispersive Solid-Phase Extraction Combined with High Performance Liquid Chromatography for the Determination of Sulfonamide Antibiotics in Environmental Water Samples

被引：0

作者：

Wen, Yuhao ^{[1
]}

Hou, Mingyang ^{[1
,2
]}

Hao, Xingkai ^{[3
]}

Sun, Dani ^{[1
,2
]}

Zhang, Hao ^{[1
]}

Saqib, Farooq ^{[3
]}

Lu, Wenhui ^{[4
]}

Liu, Huitao ^{[2
]}

Chen, Lingxin ^{[1
]}

Li, Jinhua ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Coastal Zone Ecol Environm Monitoring Technol & Eq, Shandong Res Ctr Coastal Environm Engn & Technol,S, Yantai 264003, Peoples R China

[2] Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China

[3] Zhejiang Univ, ZJU Hangzhou Global Sci & Technol Innovat Ctr, Hangzhou 311215, Peoples R China

[4] Qilu Univ Technol, Shandong Acad Sci, Fac Light Ind, Jinan 250353, Peoples R China

来源：

POLYMERS | 2024年 / 16卷 / 21期

基金：

中国国家自然科学基金;

关键词：

molecularly imprinted polymers; dual-template imprinting; sulfonamide antibiotics; dispersive solid-phase extraction; environmental water; ADSORPTION;

D O I：

10.3390/polym16213095

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In this study, we designed a molecularly imprinted polymers-dispersive solid-phase extraction-high-performance liquid chromatography (MIPs-DSPE-HPLC) method, as a simple and efficient platform for the sensitive detection of two sulfonamide antibiotics (SAs) of sulfamethoxine (SMM) and sulfamethoxazole (SMZ) in environmental water samples. Using SMM and SMZ as templates, methacrylic acid as the functional monomer, ethylene glycol dimethacrylate as the crosslinking agent, and azodiisobutyronitrile as the catalyst, the dual-template molecularly imprinted polymers (dt-MIPs) were successfully synthesized via surface imprinting technology and multi-template imprinting strategy. The adsorption properties of the prepared MIPs were characterized, and the adsorption capacities of MIPs towards SMZ and SMM were 27.35 mg/g and 30.92 mg/g, respectively. The detection limits of the method in three environmental water samples were in the range of 0.23-1.74 mu g/L, and the recoveries were between 82.7 and 110.3%, with relative standard deviations less than 5.93%. The construction process of this MIPs-DSPE-HPLC method is straightforward, exhibits high sensitivity and selectivity, and thus provides a versatile method for the quantification of SAs in complex matrices.

引用

页数：13

共 27 条

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