The design problem of fault-tolerant decentralized controllers for a class of uncertain descriptor systems is discussed. The decentralized state feedback controllers are designed using linear matrix inequalities (LMI) such that the well working order descriptor systems are asymptotical stabilization. Then the decentralized state feedback controllers are derived such that the resulting closed-loop descriptor systems are asymptotically stable when part actuators occur failure. Further the fault-tolerant decentralized state feedback controllers with integrity are presented using LMI method. Meanwhile the design approach of fault-tolerant decentralized output feedback controllers with integrity is also obtained when sensors occur fault. Therefore, the design approach of fault-tolerant decentralized controllers about actuators and sensors is obtained for a class of uncertain descriptor sysptems. Finally, designed controllers are used to electronic network systems to demonstrate their effectiveness.