RFID tag helix antenna sensors for wireless drug dosage monitoring

被引：30

作者：

Huang, Haiyu ^{[1
,2
]}

Zhao, Peisen ^{[2
,3
]}

Chen, Pai-Yen ^{[2
]}

Ren, Yong ^{[3
]}

Liu, Xuewu ^{[1
]}

Ferrari, Mauro ^{[1
]}

Hu, Ye ^{[1
]}

Akinwande, Deji ^{[2
]}

机构：

[1] Methodist Hospital Research Institute, Houston, 77030, TX

[2] Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, 78712, TX

[3] Department of Electronic Engineering, Tsinghua University, Beijing

来源：

IEEE Journal of Translational Engineering in Health and Medicine | 2014年 / 2卷 / 01期

关键词：

Drug delivery system; electrically small antenna; helix antenna; medical implants; RFID; wireless sensor;

D O I：

10.1109/JTEHM.2014.2309335

中图分类号：

学科分类号：

摘要：

Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μl/MHz for transdermal drug delivery monitoring and 2.76-μl/MHz sensitivity for implanted drug delivery monitoring. © 2015 IEEE.

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