RFID tag helix antenna sensors for wireless drug dosage monitoring

被引：30
|
作者：
Huang, Haiyu [1 ,2 ]
Zhao, Peisen [2 ,3 ]
Chen, Pai-Yen [2 ]
Ren, Yong [3 ]
Liu, Xuewu [1 ]
Ferrari, Mauro [1 ]
Hu, Ye [1 ]
Akinwande, Deji [2 ]
机构：
[1] Methodist Hospital Research Institute, Houston, 77030, TX
[2] Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, 78712, TX
[3] Department of Electronic Engineering, Tsinghua University, Beijing
来源：
IEEE Journal of Translational Engineering in Health and Medicine | 2014年 / 2卷 / 01期
关键词：
Drug delivery system; electrically small antenna; helix antenna; medical implants; RFID; wireless sensor;
D O I：
10.1109/JTEHM.2014.2309335
中图分类号：
学科分类号：
摘要：
Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μl/MHz for transdermal drug delivery monitoring and 2.76-μl/MHz sensitivity for implanted drug delivery monitoring. © 2015 IEEE.
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