Stereoselective synthesis of the C11-N26 fragment of griseoviridin

被引：8

作者：

Ghosh, Arun K. ^{[1
]}

Lei, Hui ^{[1
]}

机构：

[1] Department of Chemistry, University of Illinois, 845 West Taylor Street, Chicago, IL 60607, United States

来源：

Synthesis | 2002年 / 03期

关键词：

Acetylation; -; Catalysis; Isomers; Lipids;

D O I：

10.1055/s-2002-20037

中图分类号：

学科分类号：

摘要：

The C11-N26 fragment of griseoviridin has been prepared enantioselectively. The 1,3-syn diol synthon was derived from lipase-catalyzed selective acylation of (±)-1-(benzyloxy)pent-4-en-2-ol. The conjugated (E,E)-dienylmethyl azide functionality was installed by a Pd-catalyzed allylic azidation reaction.

引用

页码：371 / 374