Resonance raman based skin carotenoid measurements in newborns and infants

被引：25
作者：
机构：
[1] Department of Physics and Astronomy, University of Utah, Salt Lake City
[2] Department of Ophthalmology, Moran Eye Center, Salt Lake City
[3] Department of Pediatrics, Division of Neonatology, University of Utah Health Science Center, Salt Lake City
来源：
Gellermann, W. (werner@physics.utah.edu) | 1600年 / Wiley-VCH Verlag卷 / 06期
基金：
美国国家卫生研究院;
关键词：
Antioxidants; Carotenoids; Newborns; Raman spectroscopy;
D O I：
10.1002/jbio.201200195
中图分类号：
学科分类号：
摘要：
We describe Resonance Raman based skin carotenoid measurements in newborns and infants. Skin- and serum carotenoid levels correlate with high statistical significance in healthy newborns and infants, and with reduced accuracy also in prematurely born infants, who in general feature very low carotenoid levels and thin transparent skin giving rise to large background absorption effects. Skin carotenoid levels can be easily compared among subjects and/or tracked in longitudinal studies with the highly molecule-specific Raman method. It therefore holds promise as a rapid, non-invasive, carotenoid antioxidant assessment method for newborns and infants in the field of pediatrics. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：793 / 802
页数：9
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