Associations of exposure to multiple metals with blood pressure and hypertension: A cross-sectional study in Chinese preschool children

被引：0

作者：

Liu, Yanli ^{[1
,2
]}

Yu, Lili ^{[3
,4
]}

Zhu, Meiqin ^{[4
]}

Lin, Wei ^{[4
]}

Liu, Yang ^{[4
]}

Li, Mingzhu ^{[4
]}

Zhang, Yao ^{[1
,4
]}

Ji, Hongxian ^{[5
]}

Wang, Jing ^{[2
,4
]}

机构：

[1] Department of Preventive Medicine, School of Public Health and Management, Hubei University of Medicine, Hubei, Shiyan, China

[2] Department of Endocrinology, Renmin Hospital, Hubei University of Medicine, Shiyan,44200, China

[3] Dianjiang Traditional Chinese Medical Hospital, Chongqing, China

[4] Center for Environment and Health in Water Source Area of South-to-North Water, Diversion, Hubei University of Medicine, 30 Renmin South Road, Hubei, Shiyan,442000, China

[5] Department of Child Health, Shiyan Maternal and Child Health Hospital, Shiyan,44200, China

来源：

Chemosphere | 2022年 / 307卷

关键词：

Chromium concentration - Chromium irons - Cross-sectional study - Diastolic blood pressures - Hypertension - Metal models - Multi-metals - Multiple metals - Preschool children - Systolic blood pressure;

D O I：

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学科分类号：

摘要：

Exposure to metals might be a risk factor for hypertension, which contributes largely to the global burden of disease and mortality. However, relevant epidemiological studies of associations between metals exposure with hypertension among preschoolers are limited. This study aimed to explore the associations of urine metals with blood pressure and hypertension among Chinese preschoolers. A total of 1220 eligible participants who had urine metals measurement, blood pressure measurements, and relevant covariates were included in this cross-sectional study. Urine concentrations of metals were measured by inductively coupled plasma mass spectrometer. The single and multiple metals regression models were used to investigate the associations of urine metal with blood pressure and the risk of hypertension after adjusting for potential confounders. We observed urine concentrations of chromium, iron, and barium were negatively associated with levels of systolic blood pressure, diastolic blood pressure and the risk of hypertension in the single metal model (all P-FDR adjustment © 2022

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