Continuous synthesis of anisole in microreactor system

被引：0

作者：

Wang H. ^{[1
]}

Wang D. ^{[2
]}

Wang K. ^{[1
]}

Luo G. ^{[1
]}

机构：

[1] Department of Chemical Engineering, State Key Laboratory of Chemical Engineering, Tsinghua University, Beijing

[2] Shandong Peninsula Engineering Research Center of Comprehensive Brine Utilization, Weifang University of Science and Technology, Weifang, 262700, Shandong

来源：

Huagong Xuebao/CIESC Journal | 2019年 / 70卷 / 03期

关键词：

Anisole; Continuous operation; Flow; Microreactor; Mixing; Synthesis;

D O I：

10.11949/j.issn.0438-1157.20181246

中图分类号：

学科分类号：

摘要：

Anisole is an important solvent and organic synthesis intermediate. In the past, it was synthesized by batch reaction, which has problems such as low production efficiency and long operation cycle. A continuous synthesis device and technology for anisole is highly required. A continuous-flow microreaction method using sodium phenolate solution and dimethyl sulfate as reactants was proposed. The microreactor employs micromixer and locally constructive reaction tube to enhance reactant mixing and the reaction was carried out at approximately adiabatic condition. The influences of sodiumphenolate concentration, reactant flow rate and molar ratio of phenolatetodimethyl sulfate on the sodium phenolate conversion and dimethyl sulfate utility were reported. A comparison with the batch reaction in the literatures was provided to show the advantage of microreaction technology. © All Right Reserved.

引用

页码：922 / 928

页数：6

共 31 条

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