The H∞ filtering problem of discrete networked nonlinear systems with mixed random time delays and packet dropouts were investigated. The mixed random time-delays consist of network induced time delay and discrete infinite distributed delays. The network induced time delay dk takes values in a finite set, that is {dk∈ τ1τ2 …q}, the occurrence probabilities of the delays τi(i=1, 2, …, q), are known. By introducing a novel Lyapunov functional, sufficient conditions for the existence of an admissible filter are established, which ensure the asymptotical mean-square stability as well as a prescribed H∞ performance. And the filtering process is also presented. Finally, simulation results show the effectiveness of the proposed filter. ©, 2014, Central South University of Technology. All right reserved.