Advances in biosynthesis of quercetin glycoside derivatives

被引：0
|
作者：
Feng Y. [1 ,2 ,3 ]
Wang Y. [2 ,3 ]
Yao M. [1 ,2 ,3 ]
Xiao W. [2 ,3 ]
Ding M. [2 ,3 ]
机构：
[1] Frontier Technology Research Institute, Tianjin University, Tianjin
[2] Frontier Science Center for Synthetic Biology, Tianjin University, Tianjin
[3] Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin
来源：
Huagong Xuebao/CIESC Journal | 2020年 / 71卷 / 07期
关键词：
Enzyme; Metabolism; Molecular biology; Plant glycosides; Quercetin; UDP-sugars;
D O I：
10.11949/0438-1157.20200070
中图分类号：
学科分类号：
摘要：
Natural products of glycosides are the main forms of secondary metabolites in plants and have important biological activities. Glycosylation modification can change its water solubility and stability, and produce special biological activities and functions. Therefore, glycoside products are suitable for commercialization and have important medicinal and industrial values. Especially it is widely applied to anti-cancer drugs and daily chemical products, thus glycoside compounds have been concerned and studied. In recent years, the biosynthesis of glycoside products had made great progress. In this paper, the important glycoside compound quercetin is illustrated to introduce the biosynthesis of glycoside compounds, and the engineering strategy of high-yield glycoside compounds is described from the perspective of glycosyltransferase and precursor supply. It provides technological support for researchers to obtain the high-yield strains of plant glycosides by utilizing synthetic biology techniques. © All Right Reserved.
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页码：2945 / 2955
页数：10
相关论文
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