Evaluation of small animal imaging under different scan conditions

被引：0

作者：

Jia, Pengxiang ^{[1
]}

Wang, Haoyu ^{[1
,3
]}

Yan, Bin ^{[2
]}

Li, Lei ^{[2
]}

Chen, Jian ^{[2
]}

Zhang, Feng ^{[2
]}

Bao, Shanglian ^{[1
,4
]}

机构：

[1] Beijing City Key Lab of Medical Physics and Engineering, Peking University, Beijing 100871, China

[2] China National Digital Switching System Engineering and Technological Research Center, Zhengzhou 450002, China

[3] Handling Equipment Mechanical Department, Academy of Military Transportation, Tianjin 300161, China

[4] Beijing Healthware Science and Technology Inc., Beijing 100084, China

来源：

Transactions of Nanjing University of Aeronautics and Astronautics | 2010年 / 27卷 / 01期

关键词：

MATLAB - Intelligent systems - Monte Carlo methods - Computerized tomography - Animals - X ray detectors;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

To evaluae small animal imaging with individual different high voltage, filter thickness and tube current, an animal X-ray micro-computed tomography (micro-CT) system based on panel detector is developed and a rat is scanned by using the system with individual high voltage, tube current, filter thickness, and exposure time. A model is presented based on the Monte Carlo code PENELOPE for generating the X-ray spectra of X-ray tube used in the micro-CT system. A platform developed based on Matlab allows for calculating beam quality parameters, including the average energy of X-ray beam, the change of transmition rate and the input X-ray fluence. The factors affecting the signal difference to noise ratio (SDNR) of micro-CT are investigated and the relationship between SDNR and scan combinations is analyzed. A series of tools and methods are developed for small animal imaging and imaging performance evaluation in the field of small animal imaging.

引用

页码：27 / 33

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