Research progress in calcium phosphate microspheres for bone defect repair

被引：0
|
作者：
Institute of Biomaterials and Living Cell Imaging Technology, Chongqing Key Laboratory of Nano/Micro Composite Material and Device, Chongqing University of Science and Technology, Chongqing [1 ]
401331, China
机构：
[1] Institute of Biomaterials and Living Cell Imaging Technology, Chongqing Key Laboratory of Nano/Micro Composite Material and Device, Chongqing University of Science and Technology, Chongqing
来源：
Wuji Cailiao Xuebao | / 10卷 / 1009-1017期
基金：
中国国家自然科学基金;
关键词：
Bone defect repair; Calcium phosphate; Microspheres; Review;
D O I：
10.15541/jim20140010
中图分类号：
学科分类号：
摘要：
Calcium phosphate ceramic microspheres have attracted many research interests in various application fields, such as separation, catalysis, sensor, tissue engineering and drug delivery, due to their excellent permeability, high surface area ratio, low density and stable mechanical properties. In this paper, current advances of calcium phosphate ceramic microspheres in bone regeneration applications, such as bone tissue engineering and anabolic drug delivery, were comprehensively reviewed. Calcium phosphate ceramic microspheres were classified into four main categories according to their solid, porous, hollow or flow-like structures. The corresponding preparation methods and specific applications were summarized. Advantages and disadvantages of such microspheres were evaluated and future improvements were proposed. This review is intended to provide a comprehensive guide to the design and fabrication of calcium phosphate microspheres aiming at repairing bone defects.
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页码：1009 / 1017
页数：8
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