Nucleophilic substitution of the nitro group, fluorine and chlorine in aromatic compounds

被引:0
作者
Vlasov, V.M. [1 ]
机构
[1] N N Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090 Novosibirsk
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D O I
10.1070/RC2003v072n08ABEH000809
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摘要
The published data on the comparative activities of the nitro group, fluorine and chlorine in aromatic nucleophilic substitution reactions are generalised and systematised. The factors influencing the relative activities of these substituents, viz., the structure of the substrate, the nature of the nucleophile and reaction conditions, arc discussed. The synthetic applications and possible mechanisms of nucleophilic substitution of the nitro group, fluorine and chlorine in aromatic compounds are considered. The bibliography includes 265 references. © 2003 Russian Academy of Sciences and Turpion Ltd.
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页码:681 / 703
页数:22
相关论文
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