Time-resolved optical parameters determination for the finite-thickness homogeneous and layered tissue

被引：0

作者：

Yu, Biying ^{[1
,2
]}

Li, Hui ^{[1
,2
]}

机构：

[1] Fujian Provincial Key Laboratory for Photonics Technology, School of Physic and Optoelectronic Technology, Fujian Normal University, Fuzhou

[2] Key Laboratory of Optoelectronic Science and Technology for Medicine Ministry of Education, School of Physic and Optoelectronic Technology, Fujian Normal University, Fuzhou

来源：

Guangxue Xuebao/Acta Optica Sinica | 2009年 / 29卷 / SUPPL.期

关键词：

Least square fitting algorithm; Medical optics and biotechnology; Monte-Carlo simulation; Multi-distance measurements; Optical parameters determination; Time-resolved diffusion spectroscopy;

D O I：

10.3788/AOS200929S1.235

中图分类号：

学科分类号：

摘要：

The diffusion light detected from bio-tissue surface contains tissue optical parameters information. So tissue optical parameters can be obtained indirectly by the diffusion light measuring, then optical parameters resolved tissue structure, physiology and pathology state information can be obtained finally. A multi-distance measurements method is employed in this paper. A single parameter (reduced scattering coefficient) fitting method and a double parameters (reduced scattering coefficient and amplitude factor) fitting method on the basis of the least square Newton fitting algorithm is used to derive the optical parameters respectively. For the finite-thickness homogenous tissue, it can be concluded that the rest terms in expressions of diffusion reflectance and transmittance for the corresponding tissue geometries that subtract the exponential term contained source-detector distance depend on the detected position weakly. And some discussions are included. Additionally, the probable structure information for the finite-thickness two-layered slab tissue can be obtained from the diffusion reflectance and transmittance measurements according to the discrepancies of fitting reduced scattering coefficient and the sign (positive or negative) of the amplitude factor.

引用

页码：235 / 241

页数：6

共 13 条

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