Enhancing the physicochemical stability and antioxidant activity of cape gooseberry calyx extract through nanoencapsulation in soy lecithin liposomes

被引：0

作者：

Tobar-Delgado, Elizabeth ^{[1
]}

Osorio-Mora, Oswaldo ^{[2
]}

Barrera-Ocampo, Alvaro ^{[3
]}

Serna-Cock, Liliana ^{[1
]}

Salamanca, Constain H. ^{[4
,5
]}

机构：

[1] Facultad de Ingeniería y Administración, Universidad Nacional de Colombia, Carrera. 32 Chapinero, Palmira, Valle del Cauca, Colombia

[2] Facultad de Ingeniería Agroindustrial, Departamento de procesos industriales, Grupo de Investigación GAIDA, San Juan de Pasto, Colombia

[3] Grupo Natura, Departamento de Ciencias Farmacéuticas y Químicas, Facultad de Ingeniería, Diseño y Ciencias Aplicadas, Universidad ICESI, Calle 18 No. 122–135, Cali,760035, Colombia

[4] Grupo de Investigación Biopolimer, Departamento de Farmacia, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Calle 67 No. 53–108, Medellín,050010, Colombia

[5] Grupo de Investigación Ciencia de Materiales Avanzados, Escuela de Química, Facultad de Ciencias, Universidad Nacional de Colombia sede Medellín, Cra. 65 #59a-110, Medellín,050034, Colombia

来源：

Colloids and Surfaces B: Biointerfaces | 2024年 / 234卷

关键词：

Antioxidants - Efficiency - Liposomes - Oxygen - Polydispersity - Zeta potential;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The focus of this study was on the development, physicochemical characterisation and evaluation of the antioxidant activity of cape gooseberry calyx extract loaded into nanoliposomal systems. Various nanoliposomes were prepared and optimised using the ethanol injection method and characterised based on particle size, polydispersity and zeta potential measurements. Subsequently, the encapsulation efficiency and in vitro release profile of the natural antioxidant extract (NAE) were evaluated, and its antioxidant activity was assessed using the oxygen radical absorbance capacity assay. The results revealed that NAE-loaded nanoliposomes described desired quality features (e.g., particle size of −40 mV and encapsulation efficiency of ∼70%). Furthermore, it was found that NAE release is controlled by various stages, and its antioxidant activity improves by around 30% when loaded into the nanoliposomes, suggesting that it could be a promising antioxidant functional raw material. © 2023 Elsevier B.V.

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