Application of sodium sulfite and protein precipitator in heparin sodium purification

被引：0

作者：

Jiang, Yan

Zhang, Liyue

Bao, Ciguang

机构：

来源：

Huagong Xiandai/Modern Chemical Industry | 2000年 / 20卷 / 06期

关键词：

Sodium compounds - Purification - Optimization - pH - Impurities - Precipitation (chemical);

D O I：

暂无

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学科分类号：

摘要：

The optimization of Na2SO3 concentration, pH value and protein precipitator YNB99-1 dosage in heparin sodium purification is studied with the even design method. The results indicate that when the concentration of Na2SO3 is 0.07 to approximately 0.08 mol/L, the dosage of protein precipitator is 0.5 g/L and the pH value is 3.0 to approximately 3.2, impurity protein can be deleted effectively and the active yield of heparin sodium can reach 99%.

引用

页码：39 / 41