New strategies for electrochemical nucleic acid detection

被引：0

作者：

Popovich, Natasha D. ^{[1
]}

Thorp, H. Holden ^{[2
]}

机构：

[1] Home Diagnostics Inc., Fort Lauderdale, FL, United States

[2] University of NC at Chapel Hill, Chapel Hill, NC, United States

来源：

Electrochemical Society Interface | 2002年 / 11卷 / 04期

关键词：

Nucleic acid detection;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Latest strategies for electrochemical nucleic acid detection were discussed. Hybridization-based assays for single-base mismatch detection were typically limited in sensitivity by the difference in melting temperature between the duplex and the one with a single defect. Electrochemical sensors for nucleic acids offered the prospects of lower limits of detection, greater miniaturization, and the elimination of optics.

引用

页码：30 / 34