Several statistical examinations show that reducing patient trauma caused by ambulance rides could significantly improve public welfare. In this article a robot designed for active suspension of ambulance stretchers is presented. It is characterized by a special-purpose five-degree-of-freedom parallel structure. This compact mechanical architecture is able to compensate the shocks caused by road unevenness while performing pitch-and-roll rotations during accelerating, braking, and curving phases. Stretcher loading and unloading operations are considered. Direct and inverse kinematics and control strategy are discussed, and system effectiveness is shown by simulation results.