Evaluation of a chitosan-based in situ forming hydrogel

被引：0

作者：

Song, Fu-Lai ^{[1
]}

Shao, Kai ^{[1
]}

Liu, Wan-Shun ^{[1
]}

Han, Bao-Qin ^{[1
]}

Ma, Hai-Nan ^{[2
]}

机构：

[1] College of Marine Life Science, Ocean University of China

[2] Qingdao BioteMed Biomaterial Co., Ltd.

来源：

Gongneng Cailiao/Journal of Functional Materials | 2014年 / 45卷 / 09期

关键词：

Biodegradation; Chitosan; Hemostasis; In situ forming hydrogel;

D O I：

10.3969/j.issn.1001-9731.2014.09.014

中图分类号：

学科分类号：

摘要：

In situ forming hydrogels are important biomaterials in medical applications. A new class of in situ forming hydrogel derived from water-soluble chitosan and sodium alginate derivatives. The hydrogel was characterized by FT-IR spectroscopy. The surface morphology, gelation time, gel strength, swelling ratio and the pH value of the hydrogel were examined. As a potential hemostasis material, chitosan-based in situ forming hydrogel had splendid blood-control appearanced in the hemostasis experiment. The studies indicated that this hydrogel had no cytotoxicity and good histocompatibility. All the evidences provided a potential opportunity to use chitosan-based in situ forming hydrogel as a biodegradable and biocompatible hemostasis material.

引用

页码：09065 / 09069

页数：4

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