Segmentation-free x-ray energy spectrum estimation for computed tomography using dual-energy material decomposition

被引:20
|
作者
Zhao W. [1 ,2 ]
Xing L. [2 ]
Zhang Q. [1 ]
Xie Q. [1 ]
Niu T. [3 ]
机构
[1] Huazhong University of Science and Technology, Department of Biomedical Engineering, Wuhan
[2] Stanford University, Department of Radiation Oncology, Stanford, CA
[3] Zhejiang University, School of Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Hangzhou
来源
Xie, Qingguo (qgxie@hust.edu.cn) | 1600年 / SPIE卷 / 04期
关键词
Computed tomography; Cone-beam computed tomography; Dual-energy computed tomography; Least square; Material decomposition; Monte Carlo; Optimization; Spectrum estimation;
D O I
10.1117/1.JMI.4.2.023506
中图分类号
学科分类号
摘要
An x-ray energy spectrum plays an essential role in computed tomography (CT) imaging and related tasks. Because of the high photon flux of clinical CT scanners, most of the spectrum estimation methods are indirect and usually suffer from various limitations. In this study, we aim to provide a segmentation-free, indirect transmission measurement-based energy spectrum estimation method using dual-energy material decomposition. The general principle of this method is to minimize the quadratic error between the polychromatic forward projection and the raw projection to calibrate a set of unknown weights, which are used to express the unknown spectrum together with a set of model spectra. The polychromatic forward projection is performed using materialspecific images, which are obtained using dual-energy material decomposition. The algorithm was evaluated using numerical simulations, experimental phantom data, and realistic patient data. The results show that the estimated spectrum matches the reference spectrum quite well and the method is robust. Extensive studies suggest that the method provides an accurate estimate of the CT spectrum without dedicated physical phantom and prolonged workflow. This paper may be attractive for CT dose calculation, artifacts reduction, polychromatic image reconstruction, and other spectrum-involved CT applications. © 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).
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