Sacrificial functional polystyrene core template to fabricate cross-linked chitosan microcapsules

被引:0
作者
Liu W. [1 ]
Xu D. [1 ]
机构
[1] Department of Polymer Science and Engineering, School of Pharmaceutical and Chemical Engineering, Taizhou University, Linhai
关键词
32;
D O I
10.1515/epoly.2011.11.1.1
中图分类号
学科分类号
摘要
In this work, biocompatible and biodegradable chitosan microcapsules are successfully prepared in abundance and easily via using carboxyl-functionalized polystyrene (PS) particles as core template and the chitosan cross-linked with gultaraldehyde as the shell. Firstly, the monodisperse functionalized PS particles are made by emulsifier-free emulsion polymerization. The structure and morphology of the carboxyl-functionalized PS particles are characterized by FTIR, FESEM and TEM. Secondly, microcapsules are accomplished by fabricating on the basis of chemical cross-linking on the surface of the carboxyl- functionalized PS particles and by removing the core template. The microcapsules are characterized by FESEM and TEM. The results revealed that the latex particles are removed by exposure to solvent and the microcapsules exhibited the hollow structure. This work confirmed that the microcapsules are accomplished by fabricating on the basis of chemical cross-linking on the surface of the carboxyl-functionalized PS particles and by removing the core template.
引用
收藏
相关论文
共 32 条
[1]  
Du J., Chen Y., Han C., Schmidt M.J., Am. Chem. Soc., 125, (2003)
[2]  
Clark C.G., Wooley K.L., Dendrimers and Other Dendritic Polymers, (2001)
[3]  
Liggins R.T., Burt H.M., Adv. Drug. Delivery. Rev., 54, (2002)
[4]  
Peyratout C.S., Dahne L., Angew. Chem. Int. Ed., 43, (2004)
[5]  
Rogach A.L., Zebli B., Liedl T., Parak W.J., Small, 1, (2005)
[6]  
Yow H.N., Routh A.F., Soft Matter, 2, (2006)
[7]  
Yu H.Z., Jiang W., E-Polymers, 56, (2010)
[8]  
Caruso F., Caruso R.A., Mohwald H., Science, 282, (1998)
[9]  
Matthieu F.B., Bruno G.D., Skirtach A.G., Mohwald H., Sukhorukov G.B., Adv. Colloid. Interface. Sci., 158, (2010)
[10]  
Liu W.J., E-Polymers, 101, (2010)