A brief review of the modelling of the time dependent mechanical properties of tissue engineering scaffolds

被引：14
作者：
Bawolin N.K. [1 ]
Zhang W.J. [1 ]
Chen X.B. [1 ]
机构：
[1] Department of Mechanical Engineering, University of Saskatchewan, Saskatoon
来源：
Journal of Biomimetics, Biomaterials, and Tissue Engineering | 2010年 / 6卷 / 01期
关键词：
Modelling; Scaffold degradation; Time dependent mechanical properties; Tissue regeneration;
D O I：
10.4028/www.scientific.net/JBBTE.6.19
中图分类号：
学科分类号：
摘要：
The functionality of tissue scaffolds in vivo plays a critical role in the treatment process. Due to the time dependent nature of the mechanical properties of the constituent phases of the scaffold, a wide range of mechanical property histories may be observed during the treatment process, possibly influencing outcomes. The critical nature of the mechanical properties in load bearing applications indicates a need for the simultaneous modelling of both scaffold degradation and tissue regeneration with time, and the resulting effective properties of the tissue engineering construct. To this end, a review of the literature is conducted to identify the various existing approaches to modelling scaffold degradation, tissue behavior, and the dependency of the two processes on one another. © (2010) Trans Tech Publications, Switzerland.
引用
收藏
页码：19 / 33
页数：14
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