Surface modification of aliphatic polyester to enhance biocompatibility

被引：0
作者：
Bu Y. [1 ]
Ma J. [2 ,3 ]
Bei J. [1 ]
Wang S. [1 ]
机构：
[1] Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing
[2] Orthopedic Research Institute, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou
[3] Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou
来源：
Frontiers in Bioengineering and Biotechnology | 2019年 / 7卷 / MAY期
关键词：
Aliphatic polyester; Biocompatibility; Biomedical material; Surface modification; Tissue engineering;
D O I：
10.3389/fbioe.2019.98
中图分类号：
学科分类号：
摘要：
Aliphatic polyester is a kind of biodegradable implantable polymers, which shows promise as scaffolds in tissue engineering, drug carrier, medical device, and so on. To further improve its biocompatibility and cell affinity, many techniques have been used to modify the surface of the polyester. In the present paper, the key factors of influencing biocompatibility of aliphatic polyester were illuminated, and the different surface modification methods such as physical, chemical, and plasma processing methods were also demonstrated. The advantages and disadvantages of each method were also discussed with the hope that this review can serve as a resource for selection of surface modification of aliphatic products. © 2019 Bu, Ma, Bei and Wang.
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