Molecular detection of antibiotic resistance and virulence gene determinants of Enterococcus species isolated from coastal water in the Eastern Cape Province, South Africa

被引：8
作者：
Adeniji O.O. [1 ,2 ]
Sibanda T. [3 ]
Okoh A.I. [1 ,2 ]
机构：
[1] SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice
[2] Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Alice
[3] Department of Biological Sciences, University of Namibia, Windhoek
来源：
International Journal of Environmental Studies | 2020年
基金：
英国医学研究理事会;
关键词：
antibiotic resistance; Enterococcus spp; health threat; multiple antibiotic resistance; virulence factor;
D O I：
10.1080/00207233.2020.1785759
中图分类号：
学科分类号：
摘要：
Enterococci are a group of significant disease-causing bacteria, which have developed resistance to several conventionally used antibiotics. Of the 67 confirmed Enterococcus species from Kidd’s Beach, 40 (59.7%) were E. faecium, 19 (28.4%) were E. faecalis. The highest level of resistance was observed against rifampicin (83.6%) followed by erythromycin (64.2%), tetracycline (52.2%), linezolid (46.3%), tetracycline (46.3%), and vancomycin (32.8%). Ninety-six per cent of the Enterococcus spp. was found to be multi-drug resistant. MAR indices vary from 0.3 to 0.9. Two virulence determinants (ace and gelE) were detected and six resistance determinants were identified as follows: ermB (19%), tetM (30%), tetL (19%), gyrA (13%), ampC (1.5%) and Van C2/3 (4.5%). The presence of enterococci (E. faecium and E. faecalis) in Kidd’s Beach waters harbouring virulence genes that facilitate multiple antibiotic resistance signifies a possible health threat for beach goers. © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
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页码：1 / 20
页数：19
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