Research advance of degradable artificial bone with additive manufacturing: customization from geometric shape to property

被引：0
作者：
Shao H.-F. [1 ]
He Y. [1 ]
Fu J.-Z. [1 ]
机构：
[1] Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province, School of Mechanical Engineering, Zhejiang University, Hangzhou
来源：
Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science) | 2018年 / 52卷 / 06期
关键词：
3D printing; Additive manufacturing (AM); Bioactive ceramic; Bone repair; Degradable properties; Mechanical properties; Scaffold;
D O I：
10.3785/j.issn.1008-973X.2018.06.002
中图分类号：
学科分类号：
摘要：
The demand for artificial bone is increasing rapidly with the bone defect caused by frequent trauma and tumor resection. Degradable artificial bones have received significant attention in the past several years. Review the background and development status of the bone repair materials, integrated with our team's researches in the past five years. Summarize the inorganic material (bioceramics) and the domestic and international manufacturing methods about the bone repair scaffold, especially the additive manufacturing (3D printing). Focus on the mechanical properties, osteogenic capacity, degradation properties and bioactivity of the 3D printed degradable artificial bone, and discuss in a forward-looking perspective for degradable artificial bone. At present, the customization of artificial bone has transformed from geometric shape to property; personalized customization of artificial bone will be the research hotspot in future. © 2018, Zhejiang University Press. All right reserved.
引用
收藏
页码：1035 / 1057
页数：22
相关论文
共 171 条
[41]  
Kondo N., Ogose A., Tokunaga K., Et al., Bone formation and resorption of highly purified β-tricalcium phosphate in the rat femoral condyle, Biomaterials, 26, 28, pp. 5600-5608, (2005)
[42]  
Le N.D., Duval L., Lecomte A., Et al., Interactions of total bone marrow cells with increasing quantities of macroporous calcium phosphate ceramic granules, Journal of Materials Science: Materials in Medicine, 18, 10, pp. 1983-1990, (2007)
[43]  
Cho J.S., You N.K., Koo H.Y., Et al., Synthesis of nano-sized biphasic calcium phosphate ceramics with spherical shape by flame spray pyrolysis, Journal of Materials Science: Materials in Medicine, 21, 4, pp. 1143-1149, (2010)
[44]  
Wu S.C., Hsu H.C., Hsu S.K., Et al., Preparation and characterization of four different compositions of calcium phosphate scaffolds for bone tissue engineering, Materials Characterization, 62, 5, pp. 526-534, (2011)
[45]  
Yamada S., Heymann D., Bouler J.M., Et al., Osteoclastic resorption of calcium phosphate ceramics with different hydroxyapatite/beta-tricalcium phosphate ratios, Biomaterials, 18, 15, pp. 1037-1041, (1997)
[46]  
Ryu H.S., Hong K.S., Lee J.K., Et al., Magnesia-doped HA/beta-TCP ceramics and evaluation of their biocompatibility, Biomaterials, 25, 3, pp. 393-401, (2004)
[47]  
Arinzeh T.L., Tran T., Mcalary J., Et al., A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation, Biomaterials, 26, 17, pp. 3631-3638, (2005)
[48]  
Lim H.C., Song K.H., You H., Et al., Effectiveness of biphasic calcium phosphate block bone substitutes processed using a modified extrusion method in rabbit calvarial defects, Journal of Periodontal & Implant Science, 45, 2, pp. 46-55, (2015)
[49]  
Lu J., Blary M.C., Vavasseur S., Et al., Relationship between bioceramics sintering and micro-particles-induced cellular damages, Journal of Materials Science: Materials in Medicine, 15, 4, pp. 361-365, (2004)
[50]  
Xynos I.D., Edgar A.J., Buttery L.D., Et al., Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution, Journal of Biomedical Materials Research, 55, 2, pp. 151-157, (2001)
12345678910