Recent developments in bioactive ceramic/glass: Preparation and application in tissue engineering and drug delivery

被引：2

作者：

Hong Z. ^{[1
]}

机构：

[1] Physics and Astronomy Department, University of Missouri, Columbia

来源：

Recent Patents on Materials Science | 2010年 / 3卷 / 03期

关键词：

Bioactive ceramic; Bioactive glass; Biocompatible; Biodegradable; Biomaterials; Bone repair; Composite; Drug delivery; Self-assembly; Tissue engineering;

D O I：

10.2174/1874465611003030239

中图分类号：

学科分类号：

摘要：

Bioactive ceramic/glass (BCG) and its derivations have received extensive investigations and clinical applications in hard tissue substitution and regeneration. This review presents the patents on the state of art of the preparation of BCG and its application in tissue engineering and drug delivery. Most of the important patents and journal reports in last 10 years are covered in this paper. The discussions are concentrated on the preparation of various BCG materials with different architectures and functions. Special attention is paid to the recent developments in BCG cement, BCG coating, mesoporous BCG, nanoscale composite of BCG and biodegradable polymers, stimuli responsive BCG hydrogel, and homogeneously mineralized self-assembled peptide-amphiphile (PA) nanofiber-hydroxyapatite composite. Among others, development of highly ordered mesoporous BCG is highlighted as a breakthrough in the history of BCG due to its great potential in controlled delivery system for bioactive molecules in bone tissue regeneration. The nanocomposite of BCG and polymer is also considered as one of promising biomaterials due to its capability for using as the biomedical devices in load bearing bone tissue fixation and substitution. The valuable future investigations on BCG are also speculated in this review. © 2010 Bentham Science Publishers Ltd.

引用

页码：239 / 257

页数：18

共 171 条

[1]

Tamari N., Mouri M., Bioceramic Materials, (1989)

[2]

Hench L.L., Bioceramics: From concept to clinic, J Am Ceram Soc, 74, pp. 1487-1762, (1991)

[3]

Hench L.L., Bioceramics, J Am Ceram Soc, 81, pp. 1705-1728, (2005)

[4]

Liu D.M., Preparation and characterisation of porous hydroxyapatite bioceramic via a slip-casting route, Ceram Int, 24, pp. 441-446, (1998)

[5]

Mostafa A.A., Oudadesse H., Mohamed M.B., Foad E.S., Le Gal Y., Cathelineau G., Convenient approach of nanohydroxyapatite polymeric matrix composites, Chem Eng J, 153, pp. 187-192, (2009)

[6]

Nair M.B., Varma H.K., Menon K.V., Shenoy S.J., John A., Reconstruction of goat femur segmental defects using triphasic ceramic-coated hydroxyapatite in combination with autologous cells and platelet-rich plasma, Acta Biomater, 5, pp. 1742-1755, (2009)

[7]

Huang X.H., Chang J., Synthesis of nanocrystalline wollastonite powders by citrate-nitrate gel combustion method, Mater Chem Phys, 115, pp. 1-4, (2009)

[8]

Huang Y., Jin X., Zhang X., Sun H., Tu J., Tang T., Et al., In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration, Biomaterials, 30, pp. 5041-5048, (2009)

[9]

Sun H., Wu C., Dai K., Chang J., Tang T., Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite-bioactive ceramics, Biomaterials, 27, pp. 5651-5657, (2006)

[10]

Huang X.H., Chang J., Preparation of nanocrystalline bredigite powders with apatite-forming ability by a simple combustion method, Mater Res Bull, 43, pp. 1615-1620, (2008)

← 1 2 3 4 5 6 7 8 9 10 →