Copper(II) 2-(N-Tosylamino)benzaldehyde Benzoylhydrazone Complexes: Synthesis, Structures, Properties, and Biological Activity

被引：1

作者：

Chal'tsev, B. V. ^{[1
]}

Burlov, A. S. ^{[1
]}

Vlasenko, V. G. ^{[2
]}

Koshchienko, Yu. V. ^{[1
]}

Zubenko, A. A. ^{[3
]}

Klimenko, A. I. ^{[3
]}

Lazarenko, V. A. ^{[4
]}

Mashchenko, S. A. ^{[1
]}

Korshunova, E. V. ^{[1
]}

Lifintseva, T. V. ^{[5
]}

机构：

[1] Southern Fed Univ, Res Inst Phys & Organ Chem, Rostov Na Donu 344090, Russia

[2] Southern Fed Univ, Res Inst Phys, Rostov Na Donu 344090, Russia

[3] Fed Rostov Agr Res Ctr, North Caucasian Zonal Sci Res Vet Inst, Branch Fed State Budget Sci Inst, Novocherkassk, Russia

[4] Kurchatov Inst, Natl Res Ctr, Moscow, Russia

[5] Southern Fed Univ, Rostov Na Donu, Russia

来源：

RUSSIAN JOURNAL OF COORDINATION CHEMISTRY | 2024年 / 50卷 / 08期

关键词：

benzoylhydrazone; 2-(N-tosylamino)benzaldehyde; copper(II) complexes; IR spectroscopy; XRD; biological activity; TRANSITION-METAL-COMPLEXES; LANTHANIDE COMPLEXES; MAGNETIC-PROPERTIES; ANTITUMOR-ACTIVITY; CRYSTAL; NICKEL(II); COORDINATION; COBALT(II); LIGANDS; CHEMISTRY;

D O I：

10.1134/S1070328424600438

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A number of new copper(II) complexes of 2-(N-tosylamino)benzaldehyde benzoylhydrazone (H2L) CuLLn (n = 1-6) with heterocyclic donor ligands (L-1 = 1-propyl-2-aminobenzimidazole, L-2 = 1-hexyl-2-aminobenzimidazole, L-3 = 1-octyl-2-aminobenzimidazole, L-4 = 2,2'-bipyridine, L-5 = 1,10-phenanthroline, and L-6 = 2-aminopyridine) is synthesized. The structures and compositions of the synthesized compounds are determined by elemental analysis, H-1 NMR spectroscopy, IR spectroscopy, and magnetochemistry. The molecular structures of complexes CuLL1,2,4-6 are determined by XRD (CIF files CCDC nos. 2341480 (CuLL1), 2341468 (CuLL2), 2341478 (CuLL4), 2341477 (CuLL5), and 2341479 (CuLL6)). The biological activity of the complexes is studied. The adducts with L-1, L-2, and L-6 exhibit a significantly higher anti-protist activity than chloroquine used as the reference compound.

引用

页码：543 / 556

页数：14

共 49 条

[1] SYNTHESIS, STRUCTURE, AND SPECTROSCOPIC PROPERTIES OF COPPER(II) COMPOUNDS CONTAINING NITROGEN SULFUR DONOR LIGANDS - THE CRYSTAL AND MOLECULAR-STRUCTURE OF AQUA[1,7-BIS(N-METHYLBENZIMIDAZOL-2'-YL)-2,6-DITHIAHEPTANE]COPPER(II) PERCHLORATE [J].

ADDISON, AW ;

RAO, TN ;

REEDIJK, J ;

VANRIJN, J ;

VERSCHOOR, GC .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1984, (07) :1349-1356

[2] Cytotoxicity of salicylaldehyde benzoylhydrazone analogs and their transition metal complexes: quantitative structure-activity relationships [J].

Ainscough, EW ;

Brodie, AM ;

Denny, WA ;

Finlay, GJ ;

Gothe, SA ;

Ranford, JD .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1999, 77 (3-4) :125-133

[3]

[Anonymous], 2004, 42189004 MUK

[4] Novel applications of functionalized 2,1,3-benzothiadiazoles for coordination chemistry and crystal engineering [J].

Bashirov, Denis A. ;

Sukhikh, Taisiya S. ;

Kuratieva, Natalia V. ;

Chulanova, Elena A. ;

Yushina, Irina V. ;

Gritsan, Nina P. ;

Konchenko, Sergey N. ;

Zibarev, Andrey V. .

RSC ADVANCES, 2014, 4 (54) :28309-28316

[5] Electrochemical synthesis of cobalt, nickel, copper, zinc and cadmium complexes with N[(2-hydroxyphenyl)methylidine]N′-tosylbenzene-1,2-diamine.: The crystal structures of {(1,10-phenanthroline)[N-(2-oxophenyl)methylidine]-N-tosylbenzene-1,2-diaminato}nickel(II) and {(1,10-phenanthroline)[N-(2-oxophenyl)methylidine]-N′-tosylbenzene-1,2-diaminato}copper(II) [J].

Bernal, M ;

García-Vázquez, JA ;

Romero, J ;

Gómez, C ;

Durán, ML ;

Sousa, A ;

Sousa-Pedrares, A ;

Rose, DJ ;

Maresca, KP ;

Zubieta, J .

INORGANICA CHIMICA ACTA, 1999, 295 (01) :39-47

[6] Metal Complexes of Aroyl(acyl)benzoylhydrazones of Aromatic Aldehydes and Ketones: Coordination Modes and Properties [J].

Burlov, A. S. ;

Vlasenko, V. G. ;

Chal'tsev, B. V. ;

Koshchienko, Yu. V. ;

Levchenkov, S. I. .

RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2021, 47 (07) :439-472

[7] Synthesis, characterization, luminescent properties and biological activities of zinc complexes with bidentate azomethine Schiff-base ligands [J].

Burlov, A. S. ;

Vlasenko, V. G. ;

Koshchienko, Yu, V ;

Makarova, N., I ;

Zubenko, A. A. ;

Drobin, Yu D. ;

Fetisov, L. N. ;

Kolodina, A. A. ;

Zubavichus, Ya, V ;

Trigub, A. L. ;

Levchenkov, S., I ;

Garnovskii, D. A. .

POLYHEDRON, 2018, 154 :65-76

[8] Complexes of zinc(II) with N-[2-(hydroxyalkyliminomethyl)phenyl]-4-methylbenzenesulfonamides: synthesis, structure, photoluminescence properties and biological activity [J].

Burlov, A. S. ;

Vlasenko, V. G. ;

Koshchienko, Yu. V. ;

Makarova, N. I. ;

Zubenko, A. A. ;

Drobin, Yu. D. ;

Borodkin, G. S. ;

Metelitsa, A. V. ;

Zubavichus, Ya. V. ;

Garnovskii, D. A. .

POLYHEDRON, 2018, 144 :249-258

[9]

CHERNOVA NI, 1971, ZH ORG KHIM+, V7, P1680

[10] Imine coordinated 2-aminoazole complexes of (CO)5Cr(0) and (CO)5W(0), verification by structural characterisation [J].

de Jongh, Leigh-Anne ;

Strasser, Christoph E. ;

Raubenheimer, Helgard G. ;

Cronje, Stephanie .

POLYHEDRON, 2009, 28 (16) :3635-3641

← 1 2 3 4 5 →