Effect of active radical production on plasma degradation of phorbol 12-myristate 13-acetate in methanolic and aqueous solution

被引：0

作者：

Matsuura, H. ^{[1
]}

Onishi, Y. ^{[1
]}

Kongmany, S. ^{[1
,2
]}

Furuta, M. ^{[1
]}

Imamura, K. ^{[1
]}

Maeda, Y. ^{[1
]}

Okuda, S. ^{[1
]}

机构：

[1] Osaka Prefecture University, Gakuen-cho 1-2, Sakai Naka-ku

[2] National University of Laos, Vientiane Capital

来源：

Plasma Medicine | 2014年 / 4卷 / 1-4期

关键词：

Active oxygen radical; Atmospheric pressure plasma; Degradation; Phorbol; 12-myristate; 12-acetate;

D O I：

10.1615/PlasmaMed.2014011904

中图分类号：

学科分类号：

摘要：

In this study, we examine the degradation of phorbol esters with atmospheric pressure plasma and, in particular, the highly tolerant phorbol 12-myristate 13-acetate (PMA) molecule. We determined the degradation mechanism by analyzing the structural information of the by-product obtained using mass spectrometry. The plasma source was also improved to generate more active radicals, thereby enhancing the degradation of PMA. © 2014 by Begell House, Inc.

引用

页码：29 / 36

页数：7

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