Preparation of Peppermint Oil/β-CD Inclusion by High-speed Shearing with Process Optimization Using Response Surface Methodology

被引：0

作者：

Hongbin C. ^{[1
]}

Lunbo H. ^{[1
]}

Juan W. ^{[1
]}

Jianbing X. ^{[1
]}

Xiaoming Y. ^{[2
]}

Xiaohui W. ^{[1
]}

机构：

[1] Zhejiang Huisong Pharmaceutical Company Limited, Hangzhou

[2] College of Food and Biological Engineering, Jiangsu University

来源：

Science and Technology of Food Industry | 2023年 / 44卷

关键词：

Box-Behnken response surface; freeze-drying; FTIR; high-speed shearing; peppermint essential oil; β-cyclodextrin inclusion;

D O I：

10.13386/j.issn1002-0306.2023020138

中图分类号：

学科分类号：

摘要：

Objective: To investigate the optimal process for preparing peppermint essential oil/β-cyclodextrin (β-CD) inclusion complex using high-speed shearing combined with freeze-drying. Methods: The effects of freeze-drying and vacuum drying, high-speed shearing, and stirring on the encapsulation process were compared. Based on single-factor experiments, the ratio of β-CD to essential oil, encapsulation temperature, and mass fraction of β-CD were considered as influencing factors. The comprehensive score of oil content and encapsulation efficiency was used as an evaluation index to investigate the Box-Behnken response surface method for optimizing the encapsulation process. The content of pulegone in the inclusion complex was measured by high-performance liquid chromatography (HPLC). Fourier transform infrared spectroscopy (FTIR) was used to characterize the inclusion complex. Results: The yield of inclusion complex prepared by freeze-drying was higher, with an average yield of 97.6%. The oil content and encapsulation efficiency by the high-speed shearing method were relatively high, being about 3% and 19% higher than those by the stirring method, respectively. The optimized conditions were as follows: The weight ratio of β-CD to volatile oil was 9:1 (g/mL), the encapsulation temperature was 55 ℃, and the mass fraction of β-CD was 17%. Under these conditions, the essential oil content was 10.9%, the encapsulation efficiency was 97.6%, the comprehensive score was 99.7, the RSD value was 1.59%, and the optimized process was stable and feasible. The content of pulegone in the inclusion complex was found to be 2.465 mg/g by HPLC. The formation of the peppermint oil/β-CD inclusion complex was confirmed by analysis using FTIR. Conclusion: The combination of high-speed shearing and freeze-drying for the preparation of peppermint essential oil inclusion complex had the advantages of high efficiency, simple process, and it improved the yield, would provide guidance for the production process. © 2023 Editorial Department of Science and Technology of Food Science.

引用

页码：210 / 218

页数：8

共 31 条

[1]

Pharmacopoeia of the people's Republic of China (Part 1) [M], (2020)

[2]

AOKEN A, WU T, BAI X H, Et al., Comparative study of chemical composition and biological activity of essential oil from four species of mentha L. plants growing in Xinjiang by GC-MS[J], Food Research and Develop, 42, 8, pp. 127-131, (2021)

[3]

WANG F N, YU J, ZHAO C X, Et al., Optimization of preparation of Atractylodesmacrocephala volatile-β-cyclodextrin complex by response surface methodology[J], Journal of Zhejiang University, 42, 12, pp. 2160-2165, (2008)

[4]

CIOBANU A, MALLARD I, LANDY D, Et al., Retention of aroma compounds from Menthapiperitaessential oil by cyclodextrins and crosslinkedcyclodextrinpolymers[J], Food Chemistry, 138, (2013)

[5]

ZHOU Y, CHEN G, ZHAN Y, SummarizationofstudyonfoliumArtemisiaargyiessentialoilcyclodextrin complexes[J], Food Industry, 41, 8, pp. 240-243, (2020)

[6]

XU R R, GAO Y Y, ZHOU Y L, Et al., Preparation and characterization of adlay seed oil and β-cyclodextrin inclusion complexes[J], Science and Technology of Food Industry, 38, 12, pp. 258-263, (2017)

[7]

MA J Y, WANG B S, HUANG Y L., Inclusion complex of volatile oil from Thymus mongolicusronn. with hydroxypropyl-β-cyclodextrin [J], Science and Technology of Food Industry, 31, 9, pp. 259-260, (2013)

[8]

LU N, WAN X C, LIU W Q., The comprehensive evaluate of inclusion effect about peppermint oil and β-cyclodextrin with multiple-factor[J], Science and Technology of Cereals, Oils and Foods, 12, 2, (2004)

[9]

XI X H, HUANG J L, ZHANG S Y, Et al., Preparation and characterization of inclusion complex of Myristicafragrans Houtt （nutmeg） essential oil with 2-hydroxypropyl-β-cyclodextrin, Food Chemistry, 423, 15, (2023)

[10]

CHEN Q S, ZHANG H, WU J, Et al., Extraction of volatile oil from Menthehapiocalyx Briq. and processing techniques of it’s β-cycoldextrin in clusion compound[J], Journal of Yunnan University of Traditional Chinese Medicine, 31, 1, (2008)

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