The study area is the Mingde Reservoir Watershed. The main functions of this reservoir are irrigation and public water supply. It mainly supplies water for agriculture, industry and some people's livelihoods in Miaoli. In recent years, the eutrophication problem of the Mingde Reservoir is getting worse. This study applies the watershed model (SWMM) and reservoir model (Vollenweider). The purpose of this study is to analyze the pollution sources and pollution hotspots in the Mingde Reservoir Watershed. In order to protect the water quality of the Mingde Reservoir, this study proposes several pollution reduction strategies. The analysis results show that there is about 20% of point source pollution and 80% of non-point source pollution in the Mingde Reservoir watershed. Therefore, the control and reduction of non-point source pollution needs to preferentially implement in the pollution hotspots of the Mingde Reservoir Watershed. © 2020, Taiwan Agricultural Engineers Society. All rights reserved.